In the following article emphasis will be on the rising concern related to the fertility issues due to multiple factors both individually and environmentally. Different medications available in the market main emphasis on the drug Clomid and role of steroids in treating the condition. A vast majority of men buy clomid UK to overcome their infertility issues apart from other medications.
Infertility is the condition that is termed both for men and women however the criteria is different, but overall infertility is the inability to get pregnant in case of females and unable to impregnate in case of men even after one year of trying to have a baby.
The causes of infertility can be proudly classified under two sub-headings different for men and women. The two main divisions are:
· Environmental factors:
- Un-healthy surroundings and environment that is hazardous in a sense that it contains harmful chemicals and harmful rays for example some weedicides, fungicides and pesticides along with other harmful chemicals can lead to infertility.
- Prolong exposure to radiations for example people working in the radiology department or the places where there are nuclear reactors are subjected to prolong exposure to the radioactive or hazardous rays causing changes in the DNA leading to mutations and also causing fertility issue. Therefore, necessary protective gear must be worn by individuals working in such fields to ensure preservation of healthy reproductive health.
- Cigarette smoking both active smoking and passive smoking can cause fertility issues.
- Alcohol consumptions
- Unhealthy lifestyle, depression, anxiety and such disorders also cause problems with the reproductive health.
· Medical Factors:
Some medical conditions can also cause fertility problems for example:
- Deranged hormones
- Disturbed menstrual cycle
- Over or under weight
- Low testosterone levels
- Azoospermia (absence of sperms in the semen)
- Oligospermia (decreased number of sperms or low sperm count)
- Abnormal sperms (abnormalities in shape or inability to swim and so on and so forth)
INFERTILITY IN MEN:
Statistical data shows that one in every seven couple is infertile and among those infertile couple half of the infertility issues are with the men, among different factors that can cause infertile men some have been discussed above. Advancements in the field of research and technology has open many gates for such problem thus enabling the couples enjoy a healthy family life. Medications along with some clinical procedure can help men in impregnating their partners.
DRUGS OF CHOICE:
Different medicines are prescribed to men to address the issue of fertility some of the drugs used are as follows:
- Clomid or clomiphene
- Arimidex or anastrozole
- HMG stands for human menopausal gonadotropin
- HCG abbreviation of human chorionic gonadotropin
Clomid for men is the most widely used drug for treating male fertility issues that is caused by disturbed hormonal balance. It is the brand name of clomiphene citrate. The food and drug association of united states also known as FDA has not approved it for treating male infertility still it is sold off label and males buy clomid UK to treat their fertility concerns.
MECHANISM OF ACTION:
The process of increasing fertility by this drug is carried out by blocking the interaction of estrogen hormone with the pituitary gland, a pea sized gland present in the brain responsible for regulating the reproductive cycle through hormonal balance, as the pathway is blocked hence other hormones including testosterone (a primarily male sex hormone) their surge in the blood stream increases thus improving the sperm production, sperm count and decrease in the number of abnormal sperms. Thus, improving fertility.
The medication is available at the pharmacies in the form of tablets of different potency. the dosage for men is in the range of 12 milligrams per day to 400 milligrams in a day. Starting or loading dose can be prescribed up to 50 milligrams a day depending upon the severity of the situation
Individuals buy clomid UK as a off-label drug to deal with the fertility concern typically when the fertility issue is due to low levels of testosterone in the blood.
The un-wanted or adverse effects are listed below:
- Alterations in mood
- Gastro-intestinal disturbances
- Visual impairments
- Hot flushes
Steroid comprises of the synthetically or acquired from organic sources hormone look a-likes and are used widely for many reasons. Most commonly to reduce inflammatory flare-ups of the body such as asthma and auto-immune disorders and the other class is known as AAS, androgenic anabolic steroids people across the globe buy steroid UK to gain some lean body mass. These AAS are used by athletes, bodybuilders. These anabolic androgenic steroids increase the hormone testosterone levels in the body, but the problem with the increase is that it results in decrease or absence of sperms and the size of the testicles also reduces as a result fertility decreases. These drugs are also known as male contraceptive pills due to their decrease in fertility. The studies have shown that this effect on the male body is reversible and recoverable once the cessation of drug is made.
Testosterone is the hormone present both in male and female body. It is present in larger proportions in males and responsible for the sexual development and well-being. However, derangement in the hormone level can lead to fertility problems. A reduction in the natural levels can disrupt the sperms and can cause low sperm count, but Exogenous testosterone as a supplement is prescribed by the classified fitness experts to aid the bodybuilders in muscle gain through fat cutting cycles and steroid combos known as stacks, bodybuilders buy testosterone UK to gain certain type of physique but the adverse effect consists of infertility but as it is reversible so they usually take the anabolic steroids in a controlled fashion and stop the intake once target is achieved and the reversal of the infertile state also takes place after the drug is stopped.
Infertility is of a great concern in current times where un-healthy lifestyle and ingestion of steroids to achieve goals in less period of time is a common practice among men, hence leading to compromised reproductive health causing infertility. Clomid is a drug that is prescribed over the counter to treat men for infertility, but one should always consult a physician and treat the root cause.